The National Key Research and Development Plan "Blue Granary Science and Technology Innovation" key special project (hereinafter referred to as the Blue Granary Project) has made strategic arrangements in areas such as germplasm creation, healthy aquaculture, habitat restoration, environmentally friendly fishing, and green processing. This project has been implemented to promote modern fishery science and technology innovation in China, drive the transformation and upgrading of the fishery industry and green development, the establishment of a new fishery production system and its implementation. Based on bibliometrics, this study searched the publication of the Blue Granary Project in the SCIE database, and analyzed the research progress and focus of the project, including publication and citation situation of papers, research institutions, international collaboration, research directions, and high-frequency keywords, etc. The results show that since its launch in 2018 to November 7, 2023, the Blue Granary Project as the first funded project has published a total of 5,803 SCI papers, with a total citation frequency of 55,361, a total H index of 61, and ESI highly cited papers of 55, including 1 hot paper. A total of 47 nature index journal papers have been published, distributed over 15 journals, including top journals such as Nature Cell Biology, Nature Climate Change, Nature Genetics, Nature Communications, and PNAS. Shanghai Ocean University, Ocean University of China, Ningbo University, and other institutions had the most outstanding performance in terms of publication output; 951 of the papers were published by international collaboration with partners from 57 countries, with developed countries such as the United States and Australia having the highest output. The papers cover 78 research fields, mainly focusing on fishery, marine and freshwater biology, food science and technology, environmental science and ecology, chemistry, biochemistry and molecular biology, immunology, and veterinary medicine. The information retrieved from the papers shows that the Blue Granary Project has made significant progress in basic research, key core technology development, and typical application demonstration, providing theoretical support for high-quality development in aquaculture, aquaculture breeding, disease prevention and control, and aquatic product processing. The findings provide data-driven decision support for establishing a sustainable Blue Granary system, thereby advancing the high-quality development of the marine economy.