Nutrient components in the muscle of Humphead wrasse Cheilinus undulates were investigated in this paper. The results are as follows: the content of meat in whole fish was 71.5%, and the crude protein, crude fat, crude ash and moisture in fresh muscle of Humphead wrasse were 18.98 %, 1.56 %, 1.23 % and 76.23 %, respectively. Eighteen common amino acids were found in the muscle of fish and the total content of amino acids ( TAA) was 878.1mg/g (dry weight). Four kinds of delicious amino acids (DAA) were accounted for 355.3 mg/g (dry weight), and this is the main factor that the fish is delicious. The contents of EPA and DHA in fatty acids were 2.0 % and 9.51 %, respectively , EPA+DHA were 12.76% of the total fatty acids.