In order to understand the nutritive quality and nutritional components in the edible part of Anadara uropygimelana, the contents of 18 common amino acids, protein, lipids as well as vitamins and mineral ions in the soft tissue of A.uropygimelana were analyzed in this research. The results showed that the content of crude protein, crude fat, total carbohydrate and crude ash in the dry meat of A.uropygimelana were 72.67%, 1.23%, 4.44% and 11.73% respectively. Eighteen common amino acids were found in the tissue of A.uropygimelana and the total content of amino acids was 719.75mg/g in dry sample. The content of EAA was 251.23mg/g (dry weight) and the ratio of total essential amino acids to total amino acids was 34.91%, which met the FAO/WHO standards. According to nutrition evaluation in amino acids score (AAS) and chemical score (CS), the AAS of the edible part of A.uropygimelana was 107.86 with the first limiting amino acid as Val and the second limiting amino acid as Trp. The content of ω-3PUFA in fatty acids was 33.32%, which was much higher than most bivalves. The results also indicated that the edible part of A.uropygimelana was rich in water-soluble vitamins (B2, B3, B5 and C) and mineral ions such as Ca, Zn, Fe, Se, etc. The contents of heavy metals in the edible part of A.uropygimelana was low and no benzene hexachloride or DDT was detected in the sample, indicating that A.uropygimelana is safe to eat.In conclusion, the edible part of A.uropygimelana was of high nutritional value and good for human health.