| 迟潇,夏斌,朱琳,陈碧鹃,孙雪梅,赵信国,唐学玺,曲克明.BDE-47、BDE-99、BDE-153和BDE-209对蛋白核小球藻、大型溞和大菱鲆的急性毒性效应.渔业科学进展,2019,40(6):88-97 |
| In this study, we examined the biological toxicity of polybrominated diphenyl ethers, new persistent organic pollutants that can accumulate in organisms and have toxic effects in higher nutritional levels of the food chain. We performed acute toxicity tests using four polybrominated diphenyl ethers (PBDE) congeners, BDE-47, BDE-99, BDE-153, and BDE-209, on three species of marine organism, Chlorella pyrenoidosa, Daphnia magna, and Scophthalmus maximus. The 96 h concentrations for 50% maximal effect (96 h EC50) and 50% lethality (96 h LC50) were calculated for each species. The 96 h LC50 and safe concentrations of the four PBDE homologs on C. pyrenoidosa were as follows: BDE-47, 1.39 and 0.10 μg/L; BDE-99, 1.76 and 0.18 μg/L; BDE-153, 3.23 and 0.27 μg/L; and BDE-209, 378.62 and 8.68 μg/L, respectively. The 96 h LC50 and safe concentrations of the four PBDE homologs on D. magna were as follows: BDE-47, 0.24 and 0.03 μg/L; BDE-99, 1.42 and 0.82 μg/L; BDE-153, 1.49 and 0.94 μg/L; and BDE-209, 63.93 and 5.09 μg/L, respectively. The 96 h LC50 and safe concentrations of the four PBDE homologs on S. maximus were as follows: BDE-47, 5.46 and 2.02 μg/L; BDE-99, 6.07 and 2.01 μg/L; BDE-153, 7.35 and 2.17 μg/L; and BDE-209, 118.78 and 58.62 μg/L, respectively. BDE-47 was shown to be particularly toxic to marine organisms, with toxicity decreasing according to the number of Br atoms in the congener molecule in the following order: BDE-47, BDE-99, BDE-153, and BDE-209. The PBDE content of global seawater is currently at the pg/L level, whereas the 96 h EC50 and 96 h LC50 of the four homologs was at the µg/L level, much higher than the PBDE content of the marine environment. However, owing to the structural stability and environmental persistence of PBDEs, their effects on environmental health cannot be ignored, and further studies will be conducted on their toxicity. |
